Canine parvovirus belongs to the genus Parvovirus of the family Parvoviridae,It can cause severe infectious diseases in dogs. Generally, there are two clinical manifestations: hemorrhagic enteritis and Myocarditis, both of which are characterized by high mortality, high infectivity and short course of disease, especially in young age Dogs have higher rates of infection and death.
Canine Coronavirus (CCV) belongs to the genus coronaviruses of the coronavirus family,It is a very harmful infectious disease in dogs. General clinical manifestations are: gastroenteritis symptoms, with Body vomiting, diarrhea and anorexia.
CPV, CCV mixed infection, so reliable and effective detection, in the prevention and diagnosis of treatment Positive guidance.
CPV and CCV in dog feces were quantitatively detected by fluorescence immunochromatography. Basic principle Theory: Lines T and C are drawn on the nitric acid fiber membrane, and lines T1 and T2 are coated with specific CPV, Antibodies a and b of CCV antigen. There is another fluorescence that can specifically recognize CPV and CCV sprayed on the pad Nanomaterial labeled antibodies from c, d, samples of CPV, CCV first and nanomaterial labeled antibodies Body c and d are bound to form a complex, and then the complex is bound to T1 and T2 antibodies A and b. Formed sandwich structure, when the excitation light irradiation, the nanomaterials emit fluorescence signal, and the signal is strong Weak is positively correlated with CPV and CCV concentrations in samples.
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