Feline herpesvirus type I is the causative agent of feline infectious nasal bronchitis and belongs to the herpesvirus subfamily A of the herpesatidae family. General clinical manifestations: At the beginning of the disease, the main symptoms are upper respiratory tract infection. The sick cat has depression, anorexia, elevated body temperature, Cough, sneeze, tears, eyes and nose have secretions, secretions begin to be serous, as the disease worsens into pus Sex. Some sick cats appear oral ulcers, pneumonia and vaginitis, some skin ulcers. This disease is very harmful to young cats, such as If the treatment is not timely, the mortality rate can reach more than 50%. Detection of FHV IgG antibody in cats can reflect the immune status of the body.
Clinical significance:
1) For the evaluation of the body before immunization; 2) Detection of antibody titers after immunization; 3) Early in the period of feline herpes virus infection
Discovery and diagnosis.
FHV IgG antibody in cat blood was quantitatively detected by fluorescence immunochromatography. Basic principle: On nitric acid fiber membrane Lines T and C are drawn respectively. Binding pad sprayed with fluorescent nanomaterial marker that can specifically recognize FHV IgG antibody, in the sample The FHV IgG antibody first binds to the nanomaterial marker to form a complex, and then to the upper chromatography, the complex binds to the T-line, When the excitation light irradiation, the nanomaterial emits a fluorescence signal, and the strength of the signal is positively correlated with the concentration of FHV IgG antibody in the sample.
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