Canine distemper can have the following disease course:
1. Period of viremia
2. Upper respiratory tract infection virus release period
3. The inclusion body enters the kidney period
4. Period of neurological symptoms
Some diseased animals may progress to the latter two stages, at which time the relevant specimens mentioned above can be used for examination.
About 85% of canine distemper cases can be detected in eye, mouth and nose secretions, a few in the early infection or vaccine period can be detected in the blood, only a few cases in the respiratory tract can not be detected but isolated in urine or cerebrospinal fluid, usually such cases have entered a relatively late and more serious situation, the recovery is not good.
Canine distemper virus belongs to the measles disease of the parmucous virus family Poisonous genus, can cause intense infectious diseases in dogs. Detection of CDV IgG antibody in dogs It can reflect the immune condition of the body.
Clinical significance:
1) For the evaluation of the body before immunization;
2) Detection of antibody titers after immunization;
3) Early detection and diagnosis during distemper infection.
This product uses fluorescence immunochromatography to detect the CDV IgG antibody content in dog blood. Basic principle: There are T and C lines on the nitrate fiber membrane respectively. Spraying on the binding pad has energy specificity Fluorescent nanomaterial marker that identifies CDV IgG antibody, CDV IgG antibody in the sample First, it is combined with nanomaterial markers to form a complex, which is then chromatography with T Line binding, when the excitation light irradiation, the nanomaterial emit fluorescence signal, and the signal is strong Weakness was positively correlated with the concentration of CDV IgG antibody in the sample.
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