Infectious Canine Hepatitis virus (ICHV) belongs to the Adenoviridae family and can cause acute septic infections in dogs. Detection of the ICHV IgG antibody in dogs can reflect the body's immune status.
Canine Parvovirus (CPV) belongs to Parvovirus genus of Parvovirus family and can cause severe infectious diseases in dogs. Detection of the CPV IgG antibody in dogs can reflect the body's immune status.
Canine Distemper Virus (CDV) belongs to the measles virus genus of the Paramyxoviridae family and can cause severe infectious diseases in dogs. Detection of the CDV IgG antibody in dogs can reflect the body's immune status.
Canine Parainfluenza Virus (CPIV) belongs to the Paramyxoviridae family and the Paramyxovirus genus. It is a single-stranded RNA virus. Dogs infected with CPIV typically exhibit clinical symptoms such as fever, nasal discharge, and coughing, indicative of respiratory issues. Pathological changes are characterized by catarrhal rhinitis and bronchitis. Recent studies suggest that CPIV can also cause acute encephalomyelitis and hydrocephalus, with clinical manifestations including hind limb paralysis and ataxia.
Canine Coronavirus (CCV) belongs to the Coronaviridae family and the Coronavirus genus. It is a single-stranded positive-sense RNA virus. This virus can infect dogs, minks, foxes, and other canids. Dogs of all breeds, genders, and ages are susceptible, but puppies are particularly vulnerable, with an infection rate approaching 100% and a mortality rate of 50%. Infected dogs and carriers are the primary sources of transmission. The virus spreads through direct and indirect contact, infecting healthy dogs and other susceptible animals via the respiratory and digestive tracts. The disease can occur year-round but is more prevalent in winter. Factors such as sudden climate changes, poor sanitary conditions, high population density, weaning and relocation, and long-distance transportation can trigger outbreaks.
Clinical significance:
1) For pre-immunization evaluation;
2) For antibody titer detection after immunization;
3) Early detection and diagnosis of pathogenic infections.
This product utilizes fluorescence immunochromatography to quantitatively detect ICHV/CPV/CDV/CPIV/CCV IgG antibodies in dog. The basic principle is as follows: T and C lines are respectively marked on the nitrocellulose membrane. The binding pad is sprayed with fluorescent nanomaterial markers that specifically recognize five antibodies. The ICHV/CPV/CDV/CPIV/CCV IgG antibodies in the sample first combine with the nanomaterial marker to form a complex. Then, through chromatography, the complex moves upward to binds to T lines. When the test strip is irradiated by excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is positively correlated with the concentration of IgG antibodies in the sample.
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