Feline serum amyloid A is a type of cat protein Acute antiresponsive protein can be used as a sensitive indicator of systemic inflammation and a marker of tissue damage in cats During an inflammatory episode, fSAA levels in the blood rise rapidly and significantly, As inflammatory agents are cleared, the levels quickly drop back to normal. The fSAA is A non-specific reactive protein, but useful for diagnosing subclinical inflammation, detecting disease conditions and severity Emphasis, as well as observation of the therapeutic effect and process has a good guidance role, especially for antibiotics The rational use of element has suggestive effect.
fSAA content in whole blood, serum/plasma was quantitatively detected by fluorescence immunochromatography. Basic principle: There are T and C lines on the nitrate fiber embrane respectively, and the T lines are coated with specific fSAA recognition Antibody a to the antigen. The binding pad is sprayed with another fluorescent nanomaterial label that can specifically recognize fSAA The fSAA in the sample first binds to the nanomaterial labeled antibody b to form a complex. The complex then binds to the T-line antibody a to form a sandwich structure when stimulated by light During emission, the nanomaterials emit fluorescence signal, and the intensity of the signal is related to the concentration of fSAA in the sample Is positively correlated.
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