Canine distemper virus is accessory A genus of measles viruses of the mucoviral family, which can cause a highly infectious disease in dogs (Canis ), leading to clinical phenomena such as conjunctivitis, pneumonia and gastroenteritis in dogs, It is characterized by high mortality, high infectivity and a short course of disease, especially in puppies Higher rates of infection and death. So reliable, effective detection, in It has positive guiding effect on prevention, diagnosis and treatment.
The nitrocellulose membrane is marked with a test line (T) and a control line (C). The T line is coated with antibody a, which specifically recognizes CDV antigens. The conjugate pad is sprayed with fluorescent nanomaterial-labeled antibody b, another antibody that specifically binds to CDV. During testing:CDV in the sample binds to the nanomaterial-labeled antibody b, forming a complex.The complex migrates upward through the chromatographic membrane and binds to antibody a on the T line, creating a sandwich structure.When excitation light is applied, the nanomaterial emits a fluorescent signal.The signal intensity is directly proportional to the CDV concentration in the sample.
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