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Feline N-terminal Pro-Brain Natriuretic Peptide Test Kit (fNT-proBNP)
Detection Purpose
Feline N-terminal pro-brain natriuretic peptide (fNT-proBNP) is a substance secreted by cardiomyocytes in the feline ventricle, which can be used as a detection indicator for corresponding heart failure. The concentration of fNT-proBNP in the blood is related to the severity of the disease. Therefore, fNT-proBNP can not only assess the severity of acute and chronic heart failure, but also serve as an indicator of its prognosis status.
Detection Principle
This product utilizes fluorescence immunochromatography to quantitatively detect fNT-proBNP content in serum or plasma. The basic principle is as follows: T and C lines are respectively marked on the nitrocellulose membrane. The T line is coated with an antibody a that specifically recognizes fNT-proBNP. The binding pad is sprayed with another fluorescent nano-material-labeled antibody b that specifically recognizes fNT-proBNP. The fNT-proBNP in the sample first combines with the nano-material-labeled antibody b to form a complex. Then, through chromatography, the complex moves upward to binds to T line antibody a, forming a sandwich structure. When the test strip is irradiated by excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is positively correlated with the concentration of fNT-proBNP in the sample.
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